There's a big emphasis on live music, with a few specialist venues, but which pervades into most bars and clubs of the city at some point.
For an experience of local culture, check out one of several traditional restaurants with bands of old Serbia playing every night. Most other genres can be found elsewhere, from fusion funk to latin, gypsy folk to pop, and of course jazz at the annual Nišville festival.

For the rich, famous or those aspiring to such, the first stop may well be Sky cafe, and the last stop undoubtedly Studio club. If that doesn't do it for you, there are plenty of more down to earth, moreover, underground options waiting to be discovered. Živeli! (Cheers!).