Trains from Prague’s main train station run to Kutná Hora hlavní nádraží roughly every hour. Some are direct (about 50 minutes) and some are not (about 60 minutes). The indirect ones require a change in the town of Kolín. Schedules can be checked online at www.idos.cz.
The train station is about 2 kilometres from the actual town of Kutná Hora, in the suburb of Sedlec, which is conveniently where the famed Sedlec Ossuary (Bone Church) is located. There is a tourist information centre located in the train station to pick up a map and get any questions answered.

The train station is about a 10 minute walk (there are posted signs) to the Ossuary and then the town of Kutná Hora proper is another 2 kilometres from there. A tourist bus runs between the Ossuary and St. Barbara’s Cathedral in Kutná Hora. It runs whenever there are three people waiting. Check with the Sedlec Information Centre for details.

Alternatively, you can get on another train at Kutná Hora hlavní nádraží
and go to the station Kutná Hora-Sedlec, which is across the street from the Ossuary. The train, which you can take into Kutná Hora proper as well, runs about once an hour. The Kutná Hora-Sedlec station is a request stop which means you will need to push the call button in order for the train to stop at the station. There is no tourist information centre in this train station, but there is one in Sedlec.